Table 2.
Baseline characteristics of study participants from Wakiso, Uganda by sub-county
| Characteristic | Nansana (N = 696) | Busukuma (N = 259) | p-value |
|---|---|---|---|
| Median age (IQR) | 30 (24–38) | 38 (27–50) | <0.001 |
| Age group | |||
| 18–29 | 335 (48.1) | 75 (28.9) | <0.001 |
| 30–39 | 202 (29.0) | 59 (22.8) | 0.056 |
| 40–49 | 80 (11.5) | 56 (21.6) | <0.001 |
| 50–59 | 44 (6.3) | 29 (11.2) | <0.011 |
| 60+ | 35 (5.0) | 40 (15.4) | <0.001 |
| Sex | |||
| Male | 213 (30.6) | 102 (39.4) | <0.001 |
| Female | 483 (69.4) | 157 (60.6) | |
| SES | |||
| Poorest | 205 (29.4) | 21 (8.1) | <0.001 |
| Poor | 192 (27.6) | 33 (12.8) | <0.001 |
| Less poor | 126 (18.1) | 135 (52.1) | <0.001 |
| Least poor | 173 (24.9) | 70 (27.0) | 0.508 |
| Median Weight (IQR) | 62 (55–72) | 58 (50–66) | <0.001 |
| BMI groups | |||
| Underweight | 31 (4.5) | 21 (8.1) | 0.029 |
| Normal | 365 (52.4) | 179 (69.1) | <0.001 |
| Overweight | 186 (26.7) | 45 (17.4) | 0.003 |
| Obese | 114 (16.4) | 14 (5.4) | <0.001 |
| HIV-Infection | |||
| No | 622 (89.4) | 240 (92.7) | 0.126 |
| Yes | 74 (10.6) | 19 (7.3) | |
| Diabetic n (%) | |||
| Normal | 516 (74.2) | 217 (83.8) | 0.002 |
| Impaired tolerance | 139 (19.9) | 34 (13.1) | 0.015 |
| Diabetic | 41 (5.9) | 8 (3.1) | 0.082 |
| Hypertension n (%) | |||
| Normal | 535 (76.9) | 181 (69.9) | 0.026 |
| Hypertensive | 161 (23.1) | 78 (30.1) | |
| Smoking, n (%) | |||
| Never smoked | 631 (90.7) | 231 (89.2) | <0.001 |
| Previously smoker | 31 (4.4) | 8 (3.1) | 0.365 |
| Current smoker | 34 (4.9) | 20 (7.7) | 0.096 |
| Alcohol use n (%) | |||
| None | 622 (89.4) | 219 (84.6) | 0.042 |
| Mild | 23 (3.3) | 10 (3.9) | 0.652 |
| Moderate | 31 (4.5) | 21 (8.1) | 0.029 |
| Heavy | 20 (2.9) | 9 (3.5) | 0.632 |
| Mean serum creatinine (SD) | 0.65 (0.54–0.76) | 0.67 (0.53–0.81) | 0.297 |
| CG | 130 (87.7–161.5) | 112 (88.9–142.5) | <0.001 |
| MDRD | 141 (117.4–177.5) | 139 (108.5–174.7) | 0.859 |
| CKD-Epi | 139 (125.1–153.1) | 132 (114.9–147.1) | <0.001 |
| Proteinuria (urine protein ≥ 1+) | |||
| No | 693 (99.6) | 259 | 0.308 |
| Yes | 3 (0.4) | 0 | |
Socio-economic Score (SES) derived from conducting Principle Component Analysis (PCA) on a statistical software using variables relating to household infrastructure and property ownership
Abbreviations: BMI Body mass index, CG Cockroft Gault, CCr creatinine clearance, CKD-EPI Chronic Kidney Disease Epidemiology Consortium equation, IQR Interquartile range, MDRD 4-variable Modification of Diet in Renal Disease equation, SES social economic score