Table 4.

Associations^a and interactions^b between multimorbidity and self-reported health measures among working-age adults with specific musculoskeletal conditions

Sample (n = 4555)	Fair to poor health status (n = 1073) OR (95%CI)	Interaction p-valueb	High distress (n = 865) OR (95%CI)	Interaction p-value	Pain interference with activities (n = 1633) OR (95%CI)	Interaction p-value	Moderate to severe pain (n = 2086) OR (95%CI)	Interaction p-value
Any MSK (4555)	3.5 (2.7, 4.4)	-	6.0 (4.8, 7.3)	-	2.0 (1.6, 2.4)	-	1.9 (1.5, 2.3)	-
Osteoarthritis (993)	3.9 (2.2, 7.0)	0.77	6.1 (3.6, 10.2)	0.53	1.8 (1.2, 2.8)	0.56	2.1 (1.3, 3.3)	0.94
Inflammatory arthritis (317)	3.9 (1.4, 10.4)	0.27	5.4 (2.1, 14.0)	0.52	2.9 (1.3, 6.8)	0.43	2.3 (1.0, 5.3)	0.55
Other arthritis (1022)	3.4 (1.9, 5.8)	0.76	4.8 (2.8, 8.2)	0.16	1.9 (1.3, 3.0)	0.73	2.1 (1.4, 3.2)	0.82
Gout (589)	3.8 (1.8, 7.9)	0.41	7.2 (2.9, 17.9)	0.55	2.6 (1.4, 4.7)	0.54	1.7 (1.0, 2.9)	0.83
Back pain (2493)	3.8 (2.8, 5.2)	0.34	8.0 (6.0, 10.8)	<0.01	2.1 (1.6, 2.7)	0.13	2.0 (1.5, 2.7)	0.18
Soft tissue disorder (404)	4.0 (1.8, 9.0)	0.86	5.0 (2.0, 12.8)	0.36	3.3 (2.0, 5.6)	<0.05	2.1 (1.1, 3.7)	0.99
Osteoporosis (292)	5.1 (1.9, 14.0)	0.86	5.8 (2.1, 16.1)	0.37	3.4 (1.4, 8.3)	0.24	3.6 (1.5, 8.7)	0.17

legend: ^aEach row header indicates the specific MSK in which the strata-specific association between multimorbidity and each burden measure has been estimated. For each row, the reference group is those with the specific MSK but without multimorbidity. Associations (odds ratios) are adjusted for age, gender, SES, education, smoking and medium to high risk alcohol consumption. All ratings of self-reported health burden relate to the 4 weeks prior to the interview. ^bEach interaction p-value indicates whether the association between multimorbidity and the health measure differs between the specific MSK group and the remaining MSK population. Significant (p < 0.05) interactions are bolded and further details are presented textually in results section