Table 2. Cytokine/chemokine production by BM-derived macrophages from control and Eros−/− BM-derived macrophages 18 h after incubation with live S. Typhimurium M525.
Cytokines | Control | Eros−/− |
---|---|---|
pg/ml | pg/ml | |
TNF | 8,596 ± 490 | 7,564 ± 463 |
IL-12p70 | 138 ± 15 | 100 ± 15 |
KC/GRO | 6,736 ± 282 | 5,751 ± 482 |
IL-10 | 4.955 ± 182 | 5,245 ± 325 |
IL-6 | 5,497 ± 384 | 6,188 ± 571 |
IFN-γ | 41 ± 2 | 43 ± 3 |
Values presented represent the mean cytokine production in culture supernatants ± SEM. Data were analyzed by unpaired Student's t test and are representative of three independent experiments. There were no significant differences between control and Eros−/− mice in any subset studied.