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. Author manuscript; available in PMC: 2017 Apr 4.
Published in final edited form as: J Control Release. 2016 Jul 1;237:61–70. doi: 10.1016/j.jconrel.2016.06.046

Fig. 5.

Fig. 5

Dendrimer accumulation and distribution in the brain of sham fetuses at 24 h post intra-amniotic dendrimers administration. (A) Whole brain quantification shows D-OH accumulates higher than D-COOH in the brain of sham fetuses. (B) Immunofluorescence study shows different distribution of D-OH and D-COOH in the brain of sham fetuses. D-OH is mainly restricted to the blood vessels, and is not presented in the brain parenchyma, while D-COOH is minimally present. Red: D-OH or D-COOH; green: anti-CD31 labeled endothelial cells on BBB; blue: DAPI. Scale bar: top: 300 μm, bottom: 100 μm.