Figure 2. α2AP deficiency attenuated UUO-induced renal fibrosis.

(A) The kidneys at 7 days after UUO in the α2AP^+/+ and α2AP^−/− mice (Masson trichrome stain and Sirius red stain). (B) The collagen content measured by Sirius red stain in the kidneys of control and 7 days after UUO in the α2AP^+/+ and α2AP^−/− mice (n = 4). Sirius red positive area was expressed as a percent of the observed with control in the α2AP^+/+ mice. The data represent the mean ± SEM. *; P < 0.01. Scale bar = 100 μm.