Table 2.
Quantification of EV fractions and MV subtypes.
| Exosomes and MV characteristics | Median (Q1-Q3) | Range | |
|---|---|---|---|
| EV counta (106/ml PL) | Total EV (Exosomes + MV) | 1838.6 (1566.0–2321.6) | 944.4–3255.0 |
| Exosomes | 281.4 (164.7–367.8) | 55.2–818.1 | |
| MV | 1558.8 (1338.5–2030.4) | 889.2–2870.5 | |
| MV subtypesb (103/ml PL) | MVCD61+(platelets) | 264.1 (115.4–411.7) | 39.9–1427.7 |
| MVCD66+(neutrophils) | 7.8 (4.4–15.2) | 2.0–40.4 | |
| MVEpCAM+(epithelium) | 11.5 (7.0–15.7) | 3.0–41.9 | |
| MVCD105+(endothelium) | 10.9 (6.7–19.9) | 2.5–38.2 | |
| MVCD14+(macrophages/ monocytes) | 13.8 (8.0–27.8) | 2.9–113.5 | |
Q1–Q3, first quartile –third quartile.
a
Counts of EV fractions obtained by Nanosight analysis.
b
Counts of MV subtypes obtained by flow cytometry.