Figure 2. Network of known functional interactions among the up-regulated genes.

We used the STRING database⁷¹ to explore the known functional interactions among the up-regulated genes. STRING database integrates known and predicted protein interactions that are compiled from multiple sources based on high-throughput experiments, computational prediction methods, co-expression, and previous knowledge. The genes belonging to this functional network may represent the likely candidate genes that mediate the effects of music performance. Nodes represent genes and the edges represent the known functional interactions between the genes.