Figure 1.

Effect of white-fleshed peach on the excretion of nicotine metabolites and 1-hydroxypyrene in urine of smokers. Urine and saliva of subjects were collected before intake of white-fleshed peach and 4 days after intake. (A) Nicotine metabolite concentration in urine and cotinine concentration in saliva were measured by the colorimetric method and the enzyme immunoassay, respectively. (B) The 1-hydroxypyrene and creatinine concentrations in urine were measured by high-performance liquid chromatography analysis and colorimetric method, respectively. Urinary nicotine metabolite concentration and 1-hydroxypyrene concentration were corrected by salivary cotinine concentration and urinary creatinine concentration, respectively. Data are expressed as mean ± SEM. *P < 0.05 versus control (before intake).