Table 1.

Biomarker measurement methods and intra- and inter- coefficient of variation. * total samples analysed differ due to constraints on sample size and *^† where warfarin therapy may have affected protein synthesis and ^‡according to the materials available.

Biomarker	n	Measurement system	Intra- CV %	Inter- CV%
Inflammatory markers
Interleukin-6 pg/mL	1207	Randox microchip	21.0	13.4
CRP mg/L	1207	Randox microchip	5.7	11.1
NGAL ng/mL	1207	Randox microchip	4.7	9.0
TNF receptor-1 ng/mL	1205	Randox microchip	7.8	14.1
Cardiac or Neuronal function/injury
hFABP ng/mL	1205	Randox microchip	14.6	10.8
NSE ng/mL	1207	Randox microchip	7.5	20.0
BDNF pg/mL	1207	Randox microchip	9.6	11.1
Thrombotic markers
Thrombomodulin ng/mL	1207	Randox microchip	10.1	14.1
Fibrinogen g/L	1030*	Stago analyser	2.3	5.7
P-selectin ng/mL	1072*	ELISA	4.9	9.0
D-dimer μg/L	915*	Stago analyser	4.3	4.3
VWF %	1040*	Stago analyser	4.6	4.6
Protein Z ng/mL	1028*†	ELISA	4.9	14.8
Anti atherogenic antibody
Anti PC U/mL	896‡	ELISA	6.7	8.2