Figure 2.
Simulations from a Mathematical Model of the Impact of a Hypothetical Nonwaning Pre-Erythrocytic Plasmodium vivax Vaccine. (A) By preventing infection, a vaccine can reduce the expected duration of blood-stage parasitemia. Efficacy against primary infection of Vinf = 50% and duration of each blood-stage infection (primary or relapse) of 1 month are assumed. The dashed line indicates the expected duration of blood-stage parasitemia in an unvaccinated individual. (B) Predicted impact of a vaccination campaign with 70% coverage on population-level transmission. The R computer code for generating this figure is provided in the, supplemental information online allowing for simulation with different parameter values.