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. 2017 Apr 4;13(4):e1006597. doi: 10.1371/journal.pgen.1006597

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© 2017 Duchesne et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — (A) Brain. HES staining. Coronal section from Tg^-/- mouse displaying one vacuolated neuron in the lateral vestibular nucleus, indicated by an arrow (scale bar = 100 μm) (B) Nerve root from the lumbar spinal cord. Electron micrograph. Longitudinal section from Tg^-/- mouse; note the macrophage containing lipid debris, indicated by an arrow (scale bar = 2 μm). (C) Sciatic nerve, distal part. Electron micrograph. Transversal sections from WT and Tg^-/- mice. Axon diameter and myelin sheath are comparable (scale bar = 10 μm). (D) Optic nerves. Electron micrograph. Longitudinal sections from WT and Tg^-/- mice. There are no significant quantitative or qualitative differences between mitochondria of WT and Tg^-/- mice (scale bar = 1 μm). Arrowheads indicate mitochondria.