Table 1. Baseline characteristics of study subjects.
| Subjects without NAFLD (n = 160) |
Subjects with NAFLD (n = 160) |
P | |
|---|---|---|---|
| Age (years) | 52.5 (46.5, 56.5) | 52.5 (47.0, 57.0) | 0.910 |
| Sex (M:F) | 104:56 | 104:56 | 1.000 |
| BMI (kg/m2) | 23.1 (21.5, 25.0) | 25.6 (23.9, 27.9) | <0.001 |
| Waist circumference (cm) | 78 (72.5, 84) | 85 (81, 91) | <0.001 |
| Current smoker (%) | 36 (22.5) | 36 (22.5) | 1.000 |
| Alcohol consumption (%) | 95 (59.4) | 79 (49.4) | 0.073 |
| Systolic BP (mmHg) | 116 (106, 127) | 118 (111, 129.5) | 0.016 |
| Diastolic BP (mmHg) | 76 (70, 84) | 78 (70, 87) | 0.184 |
| Hemoglobin (g/dL) | 14.4 (13.1, 15.1) | 14.4 (13.5, 15.3) | 0.246 |
| WBC (103/μL) | 5.4 (4.4, 6.5) | 6.0 (5.2, 7.0) | <0.001 |
| Platelet count (103/μL) | 204 (181.0, 237.5) | 220.5 (188.5, 245.0) | 0.028 |
| BUN (mg/dL) | 13.7 (11.9, 16.6) | 15.1 (12.5, 17.4) | 0.045 |
| Creatinine (mg/dL) | 0.78 (0.62, 0.86) | 0.79 (0.64, 0.91) | 0.159 |
| Total bilirubin (mg/dL) | 0.74 (0.61, 0.99) | 0.72 (0.56, 0.93) | 0.373 |
| Albumin (g/dL) | 4.4 (4.2, 4.5) | 4.4 (4.3, 4.5) | 0.001 |
| AST (IU/L) | 23 (20, 31) | 27 (22, 37) | <0.001 |
| ALT (IU/L) | 19 (15, 26) | 30 (20, 42) | <0.001 |
| hsCRP (mg/dL) | 0.5 (0.2, 1.4) | 0.9 (0.4, 2.2) | 0.003 |
| Glucose (mmol/L) | 5.22 (4.94, 5.61) | 5.55 (5.19, 6.05) | <0.001 |
| LDL cholesterol (mmol/L) | 3.15 (2.64, 3.83) | 3.10 (2.59, 3.85) | 0.703 |
| HDL cholesterol (mmol/L) | 1.40 (1.16, 1.73) | 1.22 (1.03, 1.40) | <0.001 |
| Triglyceride (mmol/L) | 0.99 (0.67, 1.54) | 1.57 (1.03, 2.25) | <0.001 |
| Mean baPWV (m/sec) | 13.11 (12.01, 14.35) | 13.34 (12.38, 14.75) | 0.171 |
| Mean CIMT (mm) | 0.65 (0.58, 0.72) | 0.67 (0.61, 0.73) | 0.061 |
NAFLD, non-alcoholic fatty liver disease; BMI, body mass index; BP, blood pressure; WBC, white blood cell; BUN, blood urea nitrogen; AST, aspartate transaminase; ALT, alanine transaminase; hsCRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein; HDL, high-density lipoprotein; baPWV, brachial-ankle pulse wave velocity; CIMT, carotid intima-media thickness. P-values represent the results of a Mann-Whitney test or Pearson’s Chi-square test, which were conducted to detect differences between the two groups.