Table 8. DOC-Apnea results.
| Diagnostic Characteristics | Single cut-point (raw scores) | Single cut-point (regression) | Two cut-points (raw scores) | Two cut-points (regression) |
|---|---|---|---|---|
| AUC | 0.660 | 0.798 | 0.660 | 0.798 |
| High-risk | Raw score 3–4 | POI e > .19 | Raw score 4 | POI e > .43 |
| % of population | 36 (41%) | 40 (45%) | 8 (9%) | 18 (20%) |
| Impaired | 13 (36%) | 18 (45%) | 5 (63%) | 10 (55%) |
| Not Impaired | 23 (64%) | 22 (55%) | 3 (37%) | 8 (45%) |
| Specificity | 65% | 66% | 96% | 93% |
| +LR a | 1.7 | 2.5 | 5 | 3.8 |
| PPV b | 36% | 45% | 63% | 56% |
| Intermediate-risk | N/A f | N/A f | Raw score 1–3 | POI e 0.11-.43 |
| % of population | N/A f | N/A f | 73 (83%) | 36 (41%) |
| Impaired | N/A f | N/A f | 16 (22%) | 9 (25%) |
| Not Impaired | N/A f | N/A f | 57 (78%) | 27 (75%) |
| Specificity/Sensitivity | N/A f | N/A f | N/A g | N/A g |
| +/-LR ac | N/A f | N/A f | N/A g | N/A g |
| PPV/NPV bd | N/A f | N/A f | N/A g | N/A g |
| Low-risk | Raw score 0–2 | POI e < .19 | Raw score 0 | POI e < .11 |
| % of population | 52 (59%) | 48 (55%) | 7 (8%) | 34 (39%) |
| Impaired | 9 (17%) | 4 (17%) | 1 (14%) | 3 (12%) |
| Not Impaired | 43 (83%) | 44 (83%) | 6 (86%) | 31 (88%) |
| Sensitivity | 59% | 82% | 95% | 91% |
| -LR c | 0.6 | 0.3 | 1.1 | 1.6 |
| NPV d | 83% | 92% | 86% | 91% |
a +LR = positive likelihood ratio,
b PPV = positive predictive value,
c -LR = negative likelihood ratio,
d NPV = negative predictive value,
e POI = probability of impairment,
f N/A, no intermediate group using single cut-point method,
g cannot calculate statistics for intermediate group