Table 2.
aCL-positive | aβ2GPI-positive | LAC-positive n=79 |
|||
---|---|---|---|---|---|
Positive at baseline | IgG n=90 |
IgM n=29 |
IgG n=59 |
IgM n=26 |
|
| |||||
Became negative at T2** Became negative at T3*** |
6 4 |
7 0 |
14 7 |
9 2 |
15 11 |
| |||||
aCL-negative | aβ2GPI-negative |
LAC negative n=65 |
|||
Negative at baseline |
IgG n=59 |
IgM n=120 |
IgG n=89 |
IgM n=122 |
|
| |||||
Became positive at T2** Became positive at T3*** |
6 0 |
2 3 |
6 1 |
5 2 |
12 1 |
aPL-positivity is defined according to Sapporo criteria: aCL and/or aβ2GPI titers (≥40 GPL or MPL units) and/or positive LAC (RVVT, dPT, aPTT). Negative aCL or aβ2GPI titers were defined as <40 GPL or MPL units.
8 patients had APOs and their pregnancies ended before T2
26 had APOs and their pregnancies ended before T3.
Abbreviations: aCL: Anticardiolipin antibodies; aβ2GPI: anti-β2 Glycoprotein I antibodies; LAC: Lupus anticoagulant; T2: 2nd trimester of pregnancy; T3: 3rd trimester of pregnancy.