Table 1. NMR Analysis of Chow Fed 129SvEv G6pc2 KO Mouse Body Composition.
Body composition of 6 hour fasted, 16 week old animals was assessed using a mq10 NMR analyzer. Results are means ± S.E.M. obtained from the number of animals indicated in parentheses. WT=wild type; KO=knockout.
| Gender & Genotype | Body Weight (g) | Fat (g) | Muscle (g) | Free Fluid (g) | Fat (%) | Muscle (%) | Free Fluid (%) |
|---|---|---|---|---|---|---|---|
| Female WT | 22.23 ± 0.26 (15) | 2.76 ± 0.26 (11) | 13.94 ± 0.27 (11) | 0.58 ± 0.05 (11) | 13.04 ± 1.15 (11) | 66.32 ± 0.94 (11) | 2.78 ± 0.26 (11) |
| Female KO | 22.11 ± 0.54 (14) | 3.09 ± 0.46 (9) | 14.69 ± 0.25 (9), * | 0.60 ± 0.03 (9) | 13.48 ± 1.62 (9) | 66.05 ± 1.34 (9) | 2.71 ± 0.15 (9) |
| Male WT | 28.47 ± 0.34 (16) | 2.02 ± 0.35 (11) | 19.23 ± 0.37 (11) | 0.82 ± 0.10 (11) | 7.40 ± 1.29 (11) | 69.90 ± 0.91 (11) | 2.96 ± 0.25 (11) |
| Male KO | 26.93 ± 0.54 (12), * | 1.51 ± 0.25 (9) | 18.21 ± 0.38 (9) | 0.75 ± 0.12 (9) | 6.03 ± 1.00 (9) | 72.45 ± 0.96 (9) | 3.01 ± 0.51 (9) |
- Weight: *p < 0.009 male WT vs KO
- Muscle: *p < 0.04 female WT vs KO