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. Author manuscript; available in PMC: 2017 Oct 17.
Published in final edited form as: Chem Res Toxicol. 2016 Sep 9;29(10):1641–1650. doi: 10.1021/acs.chemrestox.6b00169

Figure 4. β-Glucuronidase Cleavage of Urine DBC Metabolites.

Figure 4

A. UPLC-AMS analysis of the 6–12 hour urine pool, not treated with β-glucuronidase, from a representative volunteer. Non-β-glucuronidase treated urine contains few retained metabolites and a low [14C] signal. B. UPLC-AMS analysis of urine from the same pool, treated with β-glucuronidase, contained several metabolites that were free to be extracted, separated, and detected.