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. Author manuscript; available in PMC: 2017 Oct 17.
Published in final edited form as: Chem Res Toxicol. 2016 Sep 9;29(10):1641–1650. doi: 10.1021/acs.chemrestox.6b00169

Figure 5. Urine [14C]-DBC Metabolite Profile from a Representative Volunteer over 72 Hours.

Figure 5

A. The urine [14C]-DBC metabolite profile from extracts of urine not treated with β-glucuronidase, or B. from β-glucuronidase (with sulfatase activity)-treated urine extracts. The [14C]-DBC-DHD is only present following enzyme treatment, indicating that it is in a conjugated form in urine. The putative [14C]-DBC-dione is increased following enzyme treatment only slightly, while other metabolite fractions were mostly present following enzymatic cleavage, indicating that they exist in the conjugated form in urine.