Skip to main content
. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Stroke. 2017 Feb 10;48(3):754–761. doi: 10.1161/STROKEAHA.116.015878

Figure 1. Genetic model of abundant versus sparse collaterals: congenic-B6 and congenic-Bc mice.

Figure 1

Maximally dilated pre-capillary vessels filled with Microfil shows larger collateral number in congenic (CNG)-B6 compared to CNG5-Bc. Stars, MCA-to-ACA collaterals. Inset, higher magnification showing presence and absence of pial collaterals in watershed zone. CNG-Bc, congenic-line5 wildtype BALB/cByJ mice (2±1 MCA-to-ACA collaterals of 12±13 μm lumen diameter); CNG-B6, congenic-line5 wildtype BALB/cByJ mice with C57BL/6J Dce1 genetic locus introgressed into genome (14±1 MCA-to-ACA collaterals of 20±2 μm diameter).17