Table 2.

Correlations between common genetic variant QT score and drug-induced QTc slope response

Genetic QT score vs. treatment (white subjects)	r [95% CI]	P	N	r2
Genetic score vs. Baseline QTc	0.52 [0.05 to 0.80]	0.03	17	0.27
Genetic score vs. Dofetilide QTc slope	0.55 [0.09 to 0.81]	0.02	17	0.30
Genetic score vs. Quinidine QTc slope	0.48 [−0.03 to 0.79]	0.06	16	0.23
Genetic score vs. Ranolazine QTc slope	0.52 [0.05 to 0.80]	0.03	17	0.27
Genetic QT score vs. treatment (black or African American subjects)	r [95% CI]	P	N	r2
Genetic score vs. Baseline QTc	0.97 [0.11 to 1.00]	0.03	4	0.94
Genetic score vs. Dofetilide QTc slope	0.97 [0.12 to 1.00]	0.03	4	0.94
Genetic score vs. Quinidine QTc slope	0.18 [−0.94 to 0.97]	0.82	4	0.03
Genetic score vs. Ranolazine QTc slope	0.55 [−0.87 to 0.99]	0.45	4	0.30

Fig I in the Data Supplement shows the corresponding correlation plots.