Table 3.
Drug A vs. Drug B by ECG measure (all subjects) | r [95% CI] | P | N | r2 |
---|---|---|---|---|
QTc | ||||
Dofetilide vs. Quinidine | 0.53 [0.13 to 0.78] | 0.01 | 21 | 0.28 |
Dofetilide vs. Ranolazine | 0.49 [0.09 to 0.76] | 0.02 | 22 | 0.24 |
Quinidine vs. Ranolazine | 0.53 [0.13 to 0.78] | 0.01 | 21 | 0.29 |
J-Tpeakc | ||||
Dofetilide vs. Quinidine | 0.46 [0.03 to 0.74] | 0.04 | 21 | 0.21 |
Dofetilide vs. Ranolazine | 0.54 [0.15 to 0.78] | 0.009 | 22 | 0.29 |
Quinidine vs. Ranolazine | 0.51 [0.11 to 0.77] | 0.02 | 21 | 0.26 |
Tpeak-Tend | ||||
Dofetilide vs. Quinidine | 0.72 [0.41 to 0.88] | <0.001 | 21 | 0.52 |
Dofetilide vs. Ranolazine | 0.44 [0.03 to 0.73] | 0.04 | 22 | 0.20 |
Quinidine vs. Ranolazine | 0.57 [0.19 to 0.80] | 0.007 | 21 | 0.33 |
Drug A vs. Drug B correlations computed comparing the slopes of each measure.