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Classification of CTL (CD8+ expression) and GZMB in tumor epithelium and stroma in TMA cores in two CRC patients. The following categorization was used for both biomarkers: 1 - non-detected; 2 - mild (1-10 cells per 0.28 mm2); 3 - moderate (11-29 cells per 0.28 mm2); 4 - strong infiltration (≥30 cells per 0.28 mm2).
