Table 4.

Power and Expected Sample Size: Varying Accrual

Accrual Rates	Scenario (A)	FWER	Marginal Power*					EN	ET	ENRef	ETRef
			P1	P2	P3	P4	P5
(i) (1,1,1,2,3)	0 Active	6	1	2	2	2	2	60	12.2	58	17.7
	1 Active		68	6	6	6	6	75	16.5	69	25.6
	2 Active		76	78	9	8	9	84	18.5	83	29.1
	3 Active		80	81	79	13	13	90	19.1	96	30.4
	4 Active		83	83	81	88	20	90	18.1	108	30.6
	5 Active		87	87	87	90	91	76	13.6	121	30.7
(ii) (3,2,1,1,1)	0 Active	5	3	2	2	2	2	60	11.7	58	17.7
	1 Active		79	8	8	8	8	75	16.2	69	17.5
	2 Active		86	85	16	15	16	79	16.6	83	18.5
	3 Active		88	87	82	19	18	84	17.5	96	25.9
	4 Active		87	89	84	83	27	84	16.7	108	28.8
	5 Active		90	90	85	88	87	75	13.3	121	30.6

^*Marginal error rates for inactive baskets