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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Mol Microbiol. 2017 Feb 21;104(2):306–318. doi: 10.1111/mmi.13626

Figure 5. Synergy of MB and the PfGluPho inhibitor ML304 in decreasing NADPH levels.

Figure 5

The diagram proposes how the reduction of activity of the parasite enzyme PfGluPho inhibited by ML304 cooperates with the cycles of reduction of MB via the glutathione reductase and spontaneous oxidation in reducing NADPH levels (modified from Buchholz et al., 2008).