Fig. 3. IGF-1R knockdown decreased Tam sensitivity MCF-7 cells.
A, IGF-1R expression in MCF-7 and TamR cells. B, IGF-1R expression after IGF-1R knockdown in MCF-7 cells. C, qPCR analysis of 1 µM Tam-induced IGFBP-1 transcription after IGF-1R knockdown in MCF-7 cells. * = p < 0.05, ns = not significant, and results are average or representative of three independent experiments. Error bars are SEM.