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. 2017 Apr 5;8:294. doi: 10.3389/fimmu.2017.00294

Figure 2.

Figure 2

Inflammatory responses during acute infection in naïve inflammatory macrophages and dendritic cells. Green text indicates a beneficial host effect during Mtb infection and red indicates a detrimental effect. Mtb, Mycobacterium tuberculosis; PRR, pattern recognition receptor; STING, STimulator of INterferon Genes; TBK1, tank-binding kinase 1; IRF3, interferon regulatory factor 3; 5-LO, 5-lipoxygenase; COX-2, cyclooxygenase 2; PGE2, prostaglandin E2; EP2, prostaglandin E2 receptor 2; ILC3, innate lymphoid cells type 3. 1Jayaraman et al. (97), 2Chen et al. (116), 3Shi et al. (107), 4Di Paolo et al. (98), 5Lockhart et al. (117), 6Boniface et al. (106), 7El-Behi et al. (118), 8Fremond et al. (119), 9Mishra et al. (120), 10Watson et al. (81), 11Fleetwood et al. (94), 12Mayer-Barber et al. (71), 13Antonelli et al. (72), 14Une et al. (121), 15Longhi et al. (122), 16Manca et al. (64), 17Manca et al. (65), and 18Mayer-Barber et al. (90).