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. 2016 Dec 16;13(2):299–308. doi: 10.1007/s12015-016-9708-y

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — The human-induced pluripotent stem cells (hiPSC)-derived chondrocytes: DIRECT, TGF-β3, COND and TGF-β3 + COND were analyzed by qPCR. The cells did not express Nanog, OCT4, SOX2, or E-cadherin a, the genes responsible for maintaining pluripotency. The differentiated cells expressed chondrogenic genes: type II collagen, SOX5, SOX6, SOX9 and NKX3.2 b