Figure 1.
Schematic representation of the basal hypothalamus. Ciliated ependymocytes (Ep) line the dorsal wall of the 3V. The α1d-tanycytes (α1d) and α1v-tanycytes (α1v) have long projections that make contact with the neurons of the VMN. The α2-tancycytes (α2) β1d-tanycytes (β1d) and β1v-tanycytes (β1v) make projections to the AN, making contact with orexigenic and anorexigenic neurons and blood vessels. In the floor of the 3V, the β2 lateral-tanycytes (β2la) and β2 medial-tanycytes (β2me) are joined by tight junctions forming part of the median eminence (ME)-cerebrospinal fluid (CSF) barrier, and their projections make contact with the fenestrated blood vessels of the ME. Redrawn from a previously published (Elizondo-Vega et al., 2015).