Table 2. Incidence and Factors associated with Incident HBV Infection.
Characteristics | Cases/Person years | Incidence/100 person years | Unadjusted HRs (95% CI) | p-values | Adjusted HRs (95% CI) | p-values |
---|---|---|---|---|---|---|
Overall | 39/3342 | 1.17 | ||||
Gender | ||||||
Female | 30/2381 | 1.26 | Ref | Ref | ||
Male | 9/962 | 0.94 | 0.74(0.3-1.6) | 0.434 | 0.80(0.4-1.7) | 0.573 |
AGE (years) | ||||||
40+ | 6/1239 | 0.48 | Ref | Ref | ||
30-39 | 22/1649 | 1.33 | 2.76(1.1-6.9) | <0.001 | 2.12(0.9-5.3) | 0.080 |
15-29 | 11/456 | 2.42 | 4.98(1.8-13.9) | 3.24(1.2-9.0) | ||
CD4 count* | ||||||
0-99 | 1/54 | 1.87 | Ref | |||
100-250 | 3/213 | 1.41 | 0.74(0.1-7.5) | 0.955 | ||
251-499 | 12/742 | 1.62 | 0.87(0.1-7.0) | |||
500+ | 12/921 | 1.30 | 0.70(0.1-5.6) | |||
HIV Viral load (copies/ml)** | ||||||
≤400 | 7/1175 | 0.60 | Ref | Ref | ||
>400 | 8/200 | 4.00 | 6.27(2.3-17.0) | <0.001 | 6.41(2.2-19.0) | 0.001 |
On ART | ||||||
No | 29/1288 | 2.25 | Ref | Ref | ||
Yes | 10/2055 | 0.49 | 0.21(0.1-0.4) | <0.001 | 0.25(0.1-0.5) | <0.001 |
Sex partners in last 1 year | ||||||
0 | 8/812 | 0.99 | Ref | |||
1 | 25/2091 | 1.20 | 1.21(0.5-2.7) | 0.836 | ||
>=2 | 6/440 | 1.36 | 1.38(0.5-4.1) | |||
Marital status | ||||||
Never married | 5/260 | 1.93 | Ref | |||
Married/Cohabiting | 16/1810 | 0.88 | 0.46(0.2-1.3) | 0.216 | ||
Separated/divorced/widowed | 18/1273 | 1.41 | 0.73(0.3-2.0) | |||
Occupation | ||||||
Agriculture | 22/1679 | 1.31 | Ref | |||
Fishing/Brewer/Motorcycle | 2/134 | 1.50 | 1.15(0.3-5.2) | 0.451 | ||
Trader/Formal employment | 11/804 | 1.37 | 1.06(0.5-2.2) | |||
Unemployed/Home maker | 3/220 | 1.37 | 1.04(0.3-3.6) | |||
Other | 1/508 | 0.20 | 0.15(0.0-1.1) |
377 patients had CD4 results available
262 subjects had viral load results, and 287 were on ART
ART=Antiretroviral Therapy