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. 2017 Apr 5;11:99. doi: 10.3389/fncel.2017.00099

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Copyright © 2017 Shanshan, Beibei, Li, Minna, Shipeng, Li and Yong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The efficiency of phospholipase A2 of peroxiredoxin 6 (Prdx6-iPLA2) siRNA. Effects of siRNA on mRNA (A) and protein expression (B) of Prdx6. (C) An independent phospholipase A2 (iPLA2) enzyme-linked immunosorbent assay (ELISA) kit was used to measure the PLA2 activity in microglia. (D) Both Prdx6-iPLA2 siRNA and 1-hexadecyl-3-(trifluoroethgl)-sn-glycerol-2 phosphomethanol (MJ33) had no effect on GSH activity. Values are expressed as mean ± SEM of three independent experiments, *p < 0.05 vs. Control; **p < 0.01 vs. Control; ^#p < 0.05 vs. Scramble, ^##p < 0.01 vs. Scramble.