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Effect of Prdx6-iPLA2 on Toll-like receptor 2 (TLR2) and TLR4 expression in microglia in response to OGD/R. TLR2 and TLR4 were activated during OGD/R exposure. Prdx6-iPLA2 siRNA or MJ33 treatment could inhibit TLR2 and TLR4 mRNA (A,B) and protein expression (C–E). Results are expressed as the mean ± SEM of three independent experiments. **p < 0.01 vs. Control; #p < 0.05 vs. Scramble; ##p < 0.01 vs. Scramble.
