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. 2017 Mar 10;7(3):e539. doi: 10.1038/bcj.2017.16

Figure 1.

Figure 1

Inhibition of PI3Kδ and PI3Kγ subunits in MM proliferation. (a) Western blot analysis of PI3Kδ and PI3Kγ subunits in MM cell lines and MM primary cells. Blots were probed with β-actin to show sample loading. (b) MM primary cells were treated with idelalisib (1 μm), CZC24832 (1 μm) and duvelisib (1 μm) for 72 h and then assessed for cell viability using CellTiter Glo. (c) MM primary cells were treated with idelalisib (1 μm), CZC24832 (1 μm) and duvelisib (1 μm) for 72 h and then assessed for apoptosis by PI/Annexin V staining (n=4).