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Part (A,B,C and D): the change of cytokine protein expression. In debris group, all inflammatory cytokines(IL-1β, IL-33, IL-6 and IL-8) increase, whereas LIPUS inhibits these cytokines. Part E and F: the change of FBXL2 and TRAF6 expression. Debris induces TRAF6 and inhibits FBXL2; while LIPUS inhibits TRAF6 and induces FBXL2(*p < 0.05, **p < 0.01, ***p < 0.001 vs. control group; ##p < 0.01, ###p < 0.001 vs. debris group).
