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PRC1 abrogated the G2/M-phase arrest and regulated Cip1/p21 and Kip1/p27 expression in HCC cells. (A) The cell cycle distribution in cells from different groups was analyzed by flow cytometry via PI staining. (B) The rate of G2/M phase cells from different groups was shown in histogram(*P<0.05, **P<0.01). (C) The expression levels of Cip1/p21, Kip1/p27 and the phos-pRB/p107/p130 protein levels were examined using western blot assay. β-actin was used as internal control.
