Table 4.
Multiple linear regression analysis using weight loss (%) during radiotherapy as a dependent variable
| Factors | Multiple linear regression | ||||
|---|---|---|---|---|---|
| β | SE | 95%CI | P | ||
| Step One | UICC Tumor Stage(2010) (III,IV vs. I,II) | 0.541 | 0.396 | -0.238-1.320 | 0.173 |
| Pre-RT weight (≤62.5kg vs. >62.5kg) | 1.278 | 0.447 | 0.398-2.158 | 0.005 | |
| Pretreatment albumin (≤46g/L vs. >46g/L) | 0.519 | 0.491 | -0.447-1.486 | 0.291 | |
| Chemotherapy (yes vs. no) | 0.919 | 0.723 | -0.503-2.342 | 0.205 | |
| RTOG-Skin | 0.530 | 0.373 | -0.204-1.264 | 0.156 | |
| RTOG-Mucosal | 0.883 | 0.304 | 0.285-1.482 | 0.004 | |
| RTOG-Pharynx and Esophagus | 0.995 | 0.270 | 0.464-1.525 | <0.001 | |
| RTOG-Upper G.I. | 0.588 | 0.284 | 0.030-1.146 | 0.039 | |
| Adjust R²* | 0.21 | ||||
| Step Two | Pre-RT weight (≤62.5kg vs. >62.5kg) | 1.183 | 0.454 | 0.290-2.077 | 0.01 |
| RTOG-Mucosal | 1.123 | 0.304 | 0.526-1.720 | <0.001 | |
| RTOG-Pharynx and Esophagus | 1.085 | 0.274 | 0.546-1.624 | <0.001 | |
| RTOG-Upper G.I. | 0.749 | 0.285 | 0.189-1.310 | 0.009 | |
| Adjust R²* | 0.16 | ||||
Abbreviations: SE = standard error; CI = confidence interval; UICC = Union for International Cancer Control; RT=radiotherapy; RTOG = Radiation Therapy Oncology Group.
* The model explained 21% of the variance in weight loss (%) during radiotherapy.
* The model explained 16% of the variance in weight loss (%) during radiotherapy.