Table 3.
Univariate and multivariate Cox proportional hazards analysis of overall survival for patients with bladder cancer in FUSCC cohort.
| Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age | 1.028 | 0.990 - 1.067 | 0.146 | 1.029 | 0.990 - 1.070 | 0.147 |
| Gender | 0.474 | 0.169 - 1.331 | 0.156 | 0.499 | 0.177 - 1.407 | 0.189 |
| pT stage | 1.452 | 0.967 - 2.181 | 0.072 | 1.125 | 0.702 - 1.803 | 0.624 |
| pN stagea | 1.575 | 0.774 - 3.204 | 0.210 | 1.783 | 0.849 - 3.742 | 0.126 |
| Histological grade | 1.648 | 0.509 - 5.336 | 0.404 | 1.376 | 0.393 - 4.812 | 0.617 |
| Adjuvant chemotherapy | 1.957 | 1.067 - 3.587 | 0.030 | 1.754 | 0.955 - 3.222 | 0.070 |
| Patient group | 1.069 | 0.547 - 2.088 | 0.846 | 1.006 | 0.474 - 2.135 | 0.987 |
| NR1H3 △Ct | 1.312 | 1.090 - 1.580 | 0.004 | 1.295 | 1.064 - 1.576 | 0.010 |
| NR2F6 △Ct | 0.921 | 0.766 - 1.107 | 0.381 | 0.876 | 0.720 - 1.067 | 0.189 |
a. Binary variable: No lymph node involvement versus otherwise