Table 3.
Cox proportional hazards analyses of the prognostic value of tumor residue in the 664 patients with nasopharyngeal carcinoma undergoing IMRT
| Endpoint | Variable | HR | HR (95% CI) | P-valuea |
|---|---|---|---|---|
| OS | Age (>45 vs. ≤45 years) | 2.92 | 1.59-5.36 | 0.001 |
| Residue (yes vs. no) | 2.86 | 1.62-5.04 | <0.001 | |
| PFS | Age (>45 vs. ≤45 years) | 1.59 | 1.09-2.32 | 0.017 |
| N category (N1-3 vs. N0) | 1.94 | 1.01-3.73 | 0.047 | |
| Residue (yes vs. no) | 1.61 | 1.06-2.44 | 0.026 | |
| LRFS | Residue (yes vs. no) | 2.37 | 1.35-4.15 | 0.003 |
| DMFS | Residue (yes vs. no) | NS | --- | --- |
Abbreviations: CI = confidence interval; DMFS = distant metastasis-free survival; HR = hazard ratio; IMRT = intensity-modulated radiotherapy; LRFS = locoregional relapse-free survival; NS = not significant; OS = overall survival.
a The following parameters were included in the Cox proportional hazards model multivariate analysis with backward elimination: age (> 45 vs. ≤ 45 years), gender (female vs. male), T category (T3-4 vs. T1-2), N category (N1-3 vs. N0) and chemotherapy (yes vs. no).