Table 1. Study characteristics. (OL = Olanzapine-containing groups).
Study | Ethnicity | control | Period | OL group | control group | Characteristics | ||
---|---|---|---|---|---|---|---|---|
CR | all | CR | all | |||||
Mizukami N et al. 2013 | Japanese | Vomiting control | Acute | 22 | 22 | 19 | 22 | Moderately or highly emetogenic chemotherapyC: corticosteroid + 5-HT3receptor antagonist + NK-1 receptor antagonistO: C regimen + O 5 mg/d days 0–4 |
Delayed | 22 | 22 | 16 | 22 | ||||
Overall | 22 | 22 | 15 | 22 | ||||
Navari RM et al. 2011 | American | Vomiting control | Acute | 97 | 121 | 87 | 120 | Highly emetogenic chemotherapyC: corticosteroid + 5-HT3 receptor antagonist + NK-1 receptor antagonistO: C regimen + O 10 mg/d days 1–4 |
Delayed | 77 | 121 | 73 | 120 | ||||
Overall | 77 | 121 | 73 | 120 | ||||
Nausea control | Acute | 87 | 121 | 87 | 120 | |||
Delayed | 69 | 121 | 38 | 120 | ||||
Overall | 69 | 121 | 38 | 120 | ||||
Tan L et al. 2009 | Chinese | Vomiting control | Acute | 114 | 121 | 101 | 108 | Moderately or highly emetogenic chemotherapyC:corticosteroid + 5-HT3 receptor antagonistO: C regimen + O 10 mg/d days 1–5 |
Delayed | 102 | 121 | 73 | 108 | ||||
Overall | 102 | 121 | 63 | 108 | ||||
Nausea control | Acute | 117 | 121 | 98 | 108 | |||
Delayed | 93 | 121 | 50 | 108 | ||||
Overall | 93 | 121 | 48 | 108 | ||||
WK Mao et al. 2011 | Chinese | Vomiting control | Acute | 45 | 46 | 38 | 46 | Moderately or highly emetogenic chemotherapyC: corticosteroid + 5-HT3 receptor antagonistO: C regimen + O 10 mg/d days non unspecified |
Delayed | 39 | 46 | 23 | 46 | ||||
Overall | 38 | 46 | 15 | 46 | ||||
X Wang et al. 2012 | Chinese | Vomiting control | Acute | 40 | 60 | 27 | 60 | Highly emetogenic chemotherapyC: 5-HT3 receptor antagonistO: C regimen + O 10 mg/d days 1–8 |
Delayed | 46 | 60 | 32 | 60 | ||||
Nausea control | Acute | 46 | 60 | 42 | 60 | |||
Delayed | 49 | 60 | 45 | 60 | ||||
YL Lv et al. 2013 | Chinese | Vomiting control | Overall | 22 | 30 | 11 | 30 | Moderately or highly emetogenic chemotherapyC: diphenhydramine + corticosteroid + 5-HT3 receptor antagonistO: C regimen + O 5 mg/d days 1 |