Table 2. Summary of the different comparative results. (OL = Olanzapine-containing groups; I2%: inconsistency index; Phet: P value for heterogeneity; OR = (CR in OL patient/CR in control group)/(non CR in OL patient/non CR in control group).
Control | Period | Overall or subgroup | Study number (N) | Participant (N) | OR (95%CI) | Z | P | I2 (%) | Phet |
---|---|---|---|---|---|---|---|---|---|
Vomiting control | Acute | ALL | 5 | 726 | 1.95(1.17–3.23) | 2.57 | 0.01 | 19 | 0.29 |
Chinese | 3 | 441 | 2.24(0.94–5.33) | 1.82 | 0.07 | 41 | 0.18 | ||
All excluding different criteria | 4 | 485 | 2.39(1.10–5.22) | 2.19 | 0.03 | 27 | 0.25 | ||
Delayed | ALL | 5 | 726 | 2.65(1.36–5.15) | 2.88 | 0.004 | 67 | 0.02 | |
Chinese | 3 | 441 | 3.11(2.00–4.83) | 5.03 | 0.00001 | 0 | 0.42 | ||
All excluding different criteria | 4 | 485 | 3.24(2.08–5.04) | 5.20 | 0.00001 | 2 | 0.38 | ||
Overall | ALL | 5 | 666 | 4.07(1.59–10.43) | 2.92 | 0.003 | 82 | 0.0002 | |
Chinese | 3 | 381 | 5.15(2.96–8.96) | 5.79 | 0.00001 | 21 | 0.28 | ||
All excluding different criteria | 4 | 425 | 5.38(3.14–9.20) | 6.14 | 0.00001 | 14 | 0.32 | ||
Nausea control | Acute | ALL | 3 | 590 | 1.34(0.77–2.34) | 1.03 | 0.30 | 31 | 0.23 |
Chinese | 2 | 349 | 1.80(0.90–3.59) | 1.67 | 0.10 | 4 | 0.31 | ||
All excluding different criteria | 2 | 349 | 1.80(0.90–3.59) | 1.67 | 0.10 | 4 | 0.31 | ||
Delayed | ALL | 3 | 590 | 2.79(1.76–4.43) | 4.35 | 0.0001 | 38 | 0.20 | |
Chinese | 2 | 349 | 2.54(1.01–6.42) | 1.97 | 0.05 | 69 | 0.07 | ||
All excluding different criteria | 2 | 349 | 2.54(1.01–6.42) | 1.97 | 0.05 | 69 | 0.07 | ||
Overall | ALL | 2 | 470 | 3.40(2.31–5.00) | 6.21 | 0.00001 | 0 | 0.35 |