Table 1. Baseline characteristics of included patients at time of right heart catheterisation (n = 112).
| PAH§ | CTEPH | Control | P value | |
|---|---|---|---|---|
| n = , % or mean ± SD | n = , % or mean ± SD | n = , % or mean ± SD | ||
| No. of patients | 52 | 49 | 11 | - |
| Follow-up [months] | 39.0 ± 27.6 | 39.7 ± 32.2 | - | - |
| Age [years] | 62.5 ± 10.0 | 62.4 ± 11.9 | 59.8 ± 11.6 | a 0.47b 0.51c 0.99 |
| Sex Male | 13 | 23 | 4 | a 0.50b 0.54c 0.02 |
| Female | 39 | 26 | 7 | |
| Body weight [kg] | 72.1 ± 11.0 | 78.0 ± 16.1 | 73.5 ± 15.1 | a 0.87b 0.61c 0.052 |
| Height [cm] | 164 ± 9.1 | 170 ± 9.3 | 168 ± 9.8 | a 0.48b 0.72c 0.003 |
| WHO FC I | 0 (0%) | 1 (2%) | 1 (25%) | 0.043* |
| II | 6 (12%) | 6 (13%) | 1 (25%) | |
| III | 42 (84%) | 39 (81%) | 2 (50%) | |
| IV | 2 (4%) | 2 (4%) | 0 (0%) | |
| RVSP [mm Hg] | 71.8 ± 10.2 | 79.1 ± 8.1 | 41.0# | a/b n.d.c 0.59 |
| mPAP [mm Hg] | 44.8 ± 11.3 | 45.2 ±13.9 | 13.2 ± 3.1 | a/b<0.0001c 0.86 |
| PAWP [mm Hg] | 8.8 ± 7.2 | 7.1 ± 0.7 | 7.3 ± 2.7 | a 0.28b 0.87c 0.21 |
| RAP [mm Hg] | 4.0 ± 2.6 | 5.7 ± 0.9 | - | a/b n.d.c 0.14 |
| PVR [dyne·s/cm5] | 809.6 ± 363.6 | 836.1 ± 61.5 | 105.7 ± 27.4 | a/b<0.0001c 0.90 |
| CI [l/min·m2] | 2.2 ± 0.6 | 2.1 ± 0.1 | 2.6 ± 0.3 | a 0.11b 0.08c 0.41 |
| SvO2 [%] | 65.5 ± 2.0 | 63.4 ± 1.4 | - | a/b n.d.c 0.40 |
| 6-MWD[m] | 351.7 ± 94.2 | 321.7 ± 19.8 | 550.0# | a/b n.d.c 0.21 |
| PaCO2 [kPa] | 4.4 ± 0.5 | 4.5 ± 1.0 | 5.5 ± 1.1 | a 0.001b 0.034c 0.32 |
| NT-proBNP [ng/l] | 3106.0 ± 4661.1 | 2388.0 ± 2784.6 | 240.2 ± 173.8 | a 0.0011b<0.0001c 0.43 |
| C-reactive protein [mg/l] | 11.9 ± 30.3 | 9.3 ± 9.9 | 5.9 ± 3.2 | a 0.22b 0.07c 0.60 |
| Fibrinogen [g/l] | 4.1 ± 1.4 | 4.3 ± 1.2 | 3.4 ± 0.5 | a 0.0035b 0.0006c 0.65 |
a = PAH vs. Control, b = CTEPH vs. Control, c = PAH vs. CTEPH, n.d. : not determinable; * χ2 analysis;
#single value; statistically significant p values are given in Italics. §See text for subclasses and abbreviations.