Table 3. Univariate and multivariate regression analyses of fibrinogen plasma concentrations and haemodynamic and disease severity markers in CTEPH patients.
Univariate analysis† | Multivariate analysis* | |||||
---|---|---|---|---|---|---|
Variable | R2 | Beta | P value | R2 | Beta | P value |
RAP | 0.244 | 2.309 | 0.002 | 0.269 | 2.186 | 0.008 |
mPAP | 0.137 | 4.284 | 0.011 | 0.254 | 4.047 | 0.015 |
PVR | 0.100 | 105.581 | 0.041 | 0.194 | 99.049 | 0.055 |
CI | 0.096 | −0.127 | 0.043 | 0.362 | −0.098 | 0.076 |
6-MWD | 0.113 | −31.569 | 0.048 | 0.435 | −21.129 | 0.124 |
PaCO2 | 0.096 | −0.129 | 0.058 | 0.113 | −0.115 | 0.137 |
†Univariate analysis includes plasma fibrinogen concentration and specific variable.
*Multivariate analysis includes plasma fibrinogen concentration, age, gender and WHO functional class plus specific variable. For abbreviations see text.