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Noninvasive imaging to monitor JEV replication in mouse. (A) BLI of JEV infection in BALB/c mice. Groups of 3 to 4-week-old BALB/c mice were inoculated i.p. with 107 PFU of Rluc-JEV. Imaging was performed for 90 s at the indicated times. Representative images from two mice are shown. (B) Photon flux was quantified from ROI analysis of the dorsal and ventral side. The data are representative of at least three independent experiments, and error bars indicate the standard deviation.
