Figure 4.
PET/CT imaging of macrophage migration to inflamed lesions. (a) 3D-PET/CT images and transverse PET/CT images over time. The yellow and white circles indicate the PBS- and CG-injected footpads, respectively. (b) Region of interest (ROI) analysis to determine the radioactivity in the footpads. Data represent the means ± standard deviations (SDs), n = 7. (c) Ex vivo PET/CT images of excised footpads at 6h. (d) Time-dependent bio-distribution of labeled macrophages in whole organs post-transfer. (e) The black box shows the enlarged data to clearly reveal the changes of radioactivity in CG-injected footpads. %ID/g represents percentage injected dose per gram. *P < 0.05, NS; not significant.