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HDAC6 regulates the development of IL-17-producing γδ T cells in the thymus. (A) Thymic lymphocytes were isolated from newborn WT, HDAC6 HZ, and HDAC6 KO mice. IL-17 expression in γδ T cells was analyzed by flow cytometry after stimulation with PMA and ionomycin. (B) Quantification of the percentage of IL-17-producing γδ T cells in WT, HDAC6 HZ, and HDAC6 KO mice. Data are representative of three independent experiments. Error bars indicate mean ± SEM. **p < 0.01.
