Table 1. Demographic and background data of patients and controls.
| Explaination of subjects | Group 1 (KPUM) | Group 2 (NIHS) | |
|---|---|---|---|
| a | Number of SJS/TEN patients with SOC who had taken cold medicines for treatment of common cold (CM-SJS/TEN with SOC group) | 131 | 20 |
| Female/Male | 80/51 | 14/6 | |
| Age of onset (years, mean ± SD) | 26.6 ± 17.5 | 54.0 ± 17.7 | |
| b (which are included in a) | Number of SJS/TEN patients with SOC who had taken acetaminophen for treatment of common cold (Acetaminophen-SJS/TEN with SOC group) | (59) | (14) |
| Female/Male | 37/22 | 9/5 | |
| Age of onset (years, mean ± SD) | 31.1 ± 15.8 | 35.2 ± 16.9 | |
| c | Patients with SJS/TEN without SOC who had taken cold medicines for treatment of common cold (CM-SJS/TEN without SOC group) | 16 | |
| Female/Male | - | 9/7 | |
| Age of onset (years, mean ± SD) | 62.0 ± 25.0 | ||
| d | Patients with SJS/TEN with SOC who had taken medicines not for treatment of common cold (CM unrelated-SJS/TEN with SOC group) | 14 | 38 |
| Female/Male | 11/3 | 19/19 | |
| Age of onset (years, mean ± SD) | 44.8 ± 19.3 | 57.4 ± 23.1 | |
| the samples excluded because of drug unrelated or detail unknown | 17 | - | |
| total number of the SJS/TENpatients | 162 | 74 | |
| Controls | Healthy volunteers | 419 | 220 |
| Female/Male | 350/69 | 131/89 | |
| Age (years, mean ± SD) | - | 35.5 ± 11.0 | |
CM-SJS/TEN: Cold medicine-related SJS/TEN.
SOC: severe ocular surface complications.
KPUM: Kyoto Prefectural University of Medicine, NIHS: National Institute of Health Sciences.