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. 2014 May 6;4:4851. doi: 10.1038/srep04851

Table 5. Characteristics of the studies selected in the meta-analysis.

Author Years Country Ethnicity Genotying methods Source of controls Sample size (cases/controls) Cases (TT/TG/GG) Controls (TT/TG/GG)
Alhopuro 2005 Finland European PCR-RFLP Population 969/185 334/465/170 56/98/31
Sotamaa 2005 Finland European PCR-RFLP Population 121/209 38/66/17 78/94/37
  2005 United States European PCR-RFLP Population 30/118 15/11/4 45/52/21
Menin 2006 Italy European PCR-RFLP Population 153/92 69/70/14 40/40/12
Talseth 2006 Australia and Poland European TaqMan PCR Hospital 116/98 45/57/14 40/51/7
Alazzouzi 2007 Spain European PCR-SSCP Hospital 152/184 66/69/17 97/63/24
Chen 2009 China Asian PCR-CE Population 123/138 27/66/30 29/83/26
Sugano 2010 Japan Asian LH-MSAs Population 211/59 61/95/55 12/27/20
Joshi 2011 Japan Asian PCR-RFLP Population 685/778 129/373/183 177/384/217
Chaar 2012 Tunisia European PCR-RFLP Population 167/167 11/86/70 64/56/47
Zhang 2012 China Asian MALDI-TOF MS Hospital 444/569 131/223/90 180/281/108

PCR, polymerase chain reaction; RFLP, restriction fragment length polymorphism; SSCP, single-stranded conformation polymorphism; CE, capillary electrophoresis; LH-MSAs, Loop-hybrid mobility shift assay; MALDI-TOF MS, Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry.