Titers of flu-specific serum IgG1 (A,D), serum IgG3 (B) and fold change in salivary IgA (C). Weeks 0 and 10, samples were respectively taken before Se supplementation or flu vaccination. 1, week 0; 2, week 10; 3, week 11; 4, week 12. Values are means ± SEMs for serum IgG (A,B); *different from relevant control group (P < 0.05). SeY-0/d, n = 17; SeY-50/d, n = 16; SeY-100/d, n = 19; SeY-200/d, n = 21; SeO-0/d, n = 15; SeO-50/d, n = 17. SeO, selenium onion; SeY, selenium yeast.