Carotid PET Inflammation Imaging: TIA/Stroke
Views from a 66-year-old man ([top] axial plane) and a 70-year-old man ([bottom] sagittal plane), both of whom had TIAs resulting from right internal carotid artery lesions, shown on CT (A [hatched circle], D [∗]), with intense culprit plaque inflammation (hatched circles/arrows) detected by 68Ga-DOTATATE (B, E) and reproduced by [18F]FDG (C, F). Graphs compare culprit versus nonculprit 68Ga-DOTATATE (G) and [18F]FDG (H) TBRmax values (68Ga-DOTATATE: culprit n = 14; contralateral n = 14; nonculprit [unstable CVD] n = 31; nonculprit [stable CVD] n = 24; contralateral [TIA/stroke] n = 14; diseased stable CVD n = 19; [18F]FDG: culprit n = 13; contralateral n = 13; nonculprit [unstable CVD] n = 31; nonculprit [stable CVD] n = 24; contralateral [TIA/stroke] n = 13; diseased [stable CVD] n = 19). TIA = transient ischemic attack; other abbreviations as in Figures 1, 2, and 3.