Table 1.
Baseline Clinical Factors
| Stable CVD (n = 18) | Unstable CVD∗ (n = 24) | All (n = 42) | |
|---|---|---|---|
| Age, yrs | 67 ± 10 | 71 ± 7 | 69 ± 9 |
| Male | 14 (78) | 20 (83) | 34 (81) |
| Body mass index, kg/m2 | 29 ± 5 | 27 ± 4 | 28 ± 5 |
| Heart rate, beats/min | 57 ± 9 | 58 ± 6 | 57 ± 8 |
| Systolic blood pressure, mm Hg | 141 ± 22 | 144 ± 24 | 143 ± 21 |
| Diastolic blood pressure, mm Hg | 74 ± 9 | 76 ± 10 | 75 ± 9 |
| Occurrences of previous cardiovascular history | |||
| Angina | 8 (44) | 4 (17) | 12 (29) |
| Myocardial infarction | 3 (17) | 9 (38) | 12 (29) |
| Coronary stenting | 5 (28) | 3 (13) | 8 (19) |
| Coronary artery bypass surgery | 1 (6) | 3 (13) | 4 (10) |
| Transient ischemia attack or stroke | 4 (22) | 3 (13) | 7 (17) |
| Carotid endarterectomy surgery | 2 (11) | 0 (0) | 2 (5) |
| Occurrences of cardiovascular risk factors | |||
| Hypertension | 9 (50) | 16 (67) | 25 (60) |
| Hypercholesterolemia | 17 (94) | 17 (71) | 34 (81) |
| Noninsulin dependent diabetes | 2 (11) | 6 (25) | 8 (19) |
| Smoking habit (ex or current) | 10 (56) | 18 (75) | 28 (67) |
| Family history of coronary heart disease† | 7 (39) | 12 (50) | 19 (45) |
| Occurrences of cardiovascular medications | |||
| Aspirin | 15 (83) | 15 (63) | 30 (71) |
| Clopidogrel | 6 (33) | 21 (88) | 27 (64) |
| Statin | 16 (89) | 22 (92) | 38 (91) |
| β-Adrenergic receptor blocker | 11 (61) | 14 (58) | 25 (60) |
| Angiotensin converting enzyme inhibitor/receptor blocker | 8 (44) | 17 (71) | 25 (60) |
| Calcium-channel blocker | 3 (17) | 9 (38) | 12 (29) |
| Other antihypertensive | 3 (17) | 4 (17) | 7 (17) |
| Oral nitrates | 4 (22) | 3 (13) | 7 (17) |
| Random lipid profile | |||
| Total cholesterol, mmol/l | 4.0 ± 1.1 | 3.6 ± 0.9 | 3.8 ± 0.8 |
| HDL cholesterol, mmol/l | 1.1 ± 0.2 | 1.1 ± 0.3 | 1.1 ± 0.2 |
| LDL cholesterol, mmol/l | 2.1 ± 0.6 | 1.9 ± 0.7 | 2.0 ± 0.7 |
| Triglycerides, mmol/l | 1.8 ± 0.9 | 1.3 ± 0.5 | 1.5 ± 0.7 |
| HDL cholesterol, mmol/l | 3.8 ± 1.0 | 3.4 ± 0.7 | 3.6 ± 0.9 |
| Median high-sensitivity CRP, mg/l | 2.5 (0.8–3.7) | 2.1 (0.7–5.8) | 2.4 (0.7–4.6) |
| Median peak serum troponin-I concentration, ng/l‡ | – | 573 (59.5–3,957) | – |
| Median %10-year Framingham risk score | 9 (8–21) | 18 (11–26) | 16 (8–26) |
| Median coronary artery calcium score, Agatston units | 177 (96–680) | 756 (255–1,419) | 433 (120–1,314) |
Values are mean ± SD, n (%), or mean (interquartile range).
ACS = acute coronary syndrome; CRP = C-reactive protein; CVD = cardiovascular disease; HDL = high-density lipoprotein; LDL = low-density lipoprotein; TIA = transient ischemic attack.
∗
Unstable CVD = ACS or TIA/stroke within the previous 3 months.
†
<65 years of age.
‡
ACS patients.