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. 2014 Nov 6;4:6931. doi: 10.1038/srep06931

Table 3. Comparison of the methodologies and BMAA quantitative results of environmental and food samples used in this study and previous publications.

  Methodology       Reference
Analytical method Isomers included Quantification method Instrument LOD/LOQ Method LOD/LOQ  
LC-FD DAB BMAA NR 2.0 ng/8.8 ng Brand 2010
LC-MS/MS DAB BMAA 70 fmol, i.e., 8.3 pg (S/N = 9.2)/NR NR Jonasson 2010
LC-FD and LC-MS/MS DAB and AEG BMAA in matrix NR 2.7 ng/7.0 ng (LC-FD method) Mondo 2012
LC-MS/MS DAB and AEG BMAA in matrix 5 pg (S/N = 3)/17 pg(S/N = 10) 0.5 μg/g (S/N = 3)/1.7 μg/g (S/N = 10)*** Christensen 2012
LC-MS/MS No BMAA NR NR Jiao 2013
LC-MS/MS BAMA, AEG and DAB d3-BMAA NR <0.01 μg/g (S/N = 14)/<0.01 μg/g (S/N = 44)*** this study

*Values in μg BMAA/g wet weight of tissues, others in μg BMAA/g dry weight of tissues.

**Samples from Swedish west coast.

***For comparison with other studies, the method LOD/LOQ in μg/g used in these two studies can be converted into BMAA amount by multiplying by the tissue weight, about 10 mg.

ND: not detectable; NA: not analyzed; NR: not reported; FD: fluorescent detector.