. Author manuscript; available in PMC: 2017 Sep 20.

Published in final edited form as: Eur J Pharm Sci. 2016 Jul 8;92:146–155. doi: 10.1016/j.ejps.2016.07.005

Table 2.

Particle size distributions of fresh griseofulvin nanosuspension and redispersed film samples immediately after film preparation, after 3 months of storage at 40 °C, 75% RH, and after 6 months of storage at 40 °C, 75% RH.

Formulation	d₁₀ (μm)			d₅₀ (μm)			d₉₀ (μm)
Formulation	Fresh	3 months	6 months	Fresh	3 months	6 months	Fresh	3 months	6 months
Suspension	0.099	–	–	0.159	–	–	0.262	–	–
0.0% plasticizer	0.104	0.095	0.115	0.231	0.172	0.179	0.509	0.309	0.296
2.5% glycerin	0.089	0.098	0.114	0.170	0.171	0.185	0.317	0.301	0.310
5.0% glycerin	0.092	0.091	0.113	0.166	0.166	0.190	0.305	0.306	0.328
2.5% triacetin	0.106	0.100	0.114	0.241	0.228	0.237	0.422	0.404	0.410
5.0% triacetin	0.173	0.064	0.180	0.321	0.250	0.301	0.556	0.476	0.518
2.5% PEG	0.073	0.069	0.113	0.169	0.161	0.191	0.345	0.343	0.334
5.0% PEG	0.093	0.094	0.061	0.171	0.212	0.169	0.318	0.390	0.364